Few Positives for Triple-Negative Breast Cancer
نویسندگان
چکیده
منابع مشابه
Few positives for triple-negative breast cancer.
M ost of us learned in primary school that using a double negative is bad grammar. But a disease defined by three negatives, triple-negative breast cancer (TNBC), has somehow sneaked into the oncology lexicon. Now it has a fourth negative: It is not responsive to iniparib, the poly (ADP–ribose) polymerase (PARP) inhibitor that many hoped would improve survival among patients with this recalcitr...
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Background: Previous data have shown the tumorigenicity roles of HDAC8 in breast cancer. More recently, the oncogenic effects of this molecule have been revealed in TNBC. The present study aimed to determine the diagnostic value of HDAC8 for the differentiation of TNBC from nTNBC tumors. Methods: A total of 50 cancerous and normal adjacent tumor specimens were obtained, and the clinical and pat...
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Background: Triple negative breast cancer (TNBC) is reported to be associated with a high risk of recurrence, poor overall survival (OS), and disease-free survival (DFS) rates. This study evaluated the clincopathological features and survival of non-metastatic TNBC women in the capital of Iran compared with other areas of the world. Methods: In a retrospective study, 119 women with TNBC based ...
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From the Program in Cancer Genetics, the Research Institute of the McGill University Health Centre, and the Lady Davis Institute of the Jewish General Hospital (W.D.F.); McGill University, Montreal; and the Breast Unit, Royal Marsden Hospital and Institute of Cancer Research (I.E.S.), and the Breakthrough Breast Cancer Research Centre, Institute of Cancer Research (J.S.R.-F.) — both in London. ...
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ژورنال
عنوان ژورنال: JNCI Journal of the National Cancer Institute
سال: 2011
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djr120